Competent Cells Market

Global Competent Cells Market Size, Share & Trends Analysis Report By Type, By Application (Cloning, Protein Expression, Mutagenesis, and Others), By End-Use, By Regional Outlook and Forecast, 2024 - 2031

Report Id: KBV-23708 Publication Date: July-2024 Number of Pages: 327
2023
USD 2.0 Billion
2031
USD 3.7 Billion
CAGR
7.9%
Historical Data
2020 to 2022

“Global Competent Cells Market to reach a market value of USD 3.7 Billion by 2031 growing at a CAGR of 7.9%”

Analysis of Market Size & Trends

The Global Competent Cells Market size is expected to reach $3.7 billion by 2031, rising at a market growth of 7.9% CAGR during the forecast period.

Rising healthcare expenditures in Asia Pacific countries fuel demand for innovative biopharmaceuticals, personalized medicine, and diagnostic tools. These cells are essential in developing these healthcare solutions, contributing to market growth. Consequently, the Asia Pacific region would acquire nearly 30% of the total market share by 2031.

Competent Cells Market Size - Global Opportunities and Trends Analysis Report 2020-2031

Recombinant DNA technology is fundamental for cloning and expressing genes in host cells. These cells are essential for introducing recombinant DNA into bacterial cells to produce therapeutic proteins, enzymes, and vaccines. In addition, the development of personalized medicine, which tailors’ treatments based on individual genetic profiles, relies on recombinant DNA technology and these cells. Hence, the growing demand for recombinant DNA technology drives the market's growth.

Additionally, these cells are essential for introducing and expressing genes of interest to study their functions. Researchers use these cells to clone specific genes, manipulate DNA sequences, and explore gene interactions, which are fundamental in understanding biological processes and disease mechanisms. Thus, the expansion of genomic and proteomic studies is propelling the market's growth.

Moreover, the pandemic spurred heightened demand for these cells as pharmaceutical and biotech companies accelerated research and development efforts for vaccines and therapies. Also, companies in the competent cells sector adapted quickly to ensure uninterrupted supply chains, enhancing market stability and growth during the pandemic. Thus, the COVID-19 pandemic had a positive impact on the market.

However, establishing a competent cell production facility requires significant investment in specialized equipment such as bioreactors, incubators, purification systems, and sterile facilities. Moreover, scaling up production from laboratory-scale to commercial quantities can involve additional costs related to process optimization, validation, and facility expansion. Hence, high initial costs are hindering the growth of the market.

Driving and Restraining Factors
Competent Cells Market
  • Growing demand for recombinant DNA technology
  • Expansion of genomic and proteomic studies
  • Growth of biotechnology and pharmaceutical industries
  • High initial costs
  • Limited shelf life of competent cells
  • Rising regenerative medicine and cell therapy
  • Increasing government and private funding
  • Increasing competition from alternative technologies
  • Quality control and standardization issues

Type Outlook

Based on type, the market is divided into chemically competent cells, electrocompetent cells, and ultracompetent cells. The electrocompetent cells segment attained 34% revenue share in the market in 2023. Electrocompetent cells typically offer higher transformation efficiencies compared to chemically competent cells. This makes them suitable for applications that require precise control over transformation efficiency, such as gene editing, library construction, and high-throughput screening.

Application Outlook

On the basis of application, the market is segmented into cloning, protein expression, mutagenesis, and others. In 2023, the protein expression segment attained a 24% revenue share in the market. These cells with high transformation efficiencies and robust protein expression capabilities are preferred for generating large quantities of recombinant proteins.

Competent Cells Market Share and Industry Analysis Report 2023

End-Use Outlook

By end-use, the market is divided into pharmaceutical & biotechnology companies, academic & research institutes, and others. The academic & research institutes segment procured a 37% revenue share in the market in 2023. These cells are fundamental tools in molecular biology research for studying gene function, protein expression, and genetic pathways. Academic institutions use these cells to conduct basic research that advances our understanding of biological processes and diseases.

Free Valuable Insights: Global Competent Cells Market size to reach USD 3.7 Billion by 2031

Regional Outlook

Region-wise, the market is analyzed across North America, Europe, Asia Pacific, and LAMEA. The North America region witnessed 35% revenue share in the market in 2023. North America hosts some of the world’s leading biotechnology and pharmaceutical companies, particularly the United States and Canada. These industries drive substantial demand for these cells for research, development, and production of biopharmaceuticals, vaccines, and therapeutic proteins.

Competent Cells Market Report Coverage
Report Attribute Details
Market size value in 2023 USD 2.0 Billion
Market size forecast in 2031 USD 3.7 Billion
Base Year 2023
Historical Period 2020 to 2022
Forecast Period 2024 to 2031
Revenue Growth Rate CAGR of 7.9% from 2024 to 2031
Number of Pages 237
Tables 360
Report coverage Market Trends, Revenue Estimation and Forecast, Segmentation Analysis, Regional and Country Breakdown, Porter’s 5 Forces Analysis, Company Profiling, Companies Strategic Developments, SWOT Analysis, Winning Imperatives
Segments covered Type, Application, End-Use, Region
Country scope
  • North America (US, Canada, Mexico, and Rest of North America)
  • Europe (Germany, UK, France, Russia, Spain, Italy, and Rest of Europe)
  • Asia Pacific (China, Japan, India, South Korea, Australia, Malaysia, and Rest of Asia Pacific)
  • LAMEA (Brazil, Argentina, UAE, Saudi Arabia, South Africa, Nigeria, and Rest of LAMEA)
Companies Included Thermo Fisher Scientific, Inc., Merck KGaA, Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Promega Corporation, New England Biolabs, Inc., Qiagen N.V, F. Hoffmann-La Roche Ltd., Takara Bio Inc. (Takara Holdings Inc.) and Lonza Group Ltd. (Capsugel)
 
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  • Jun-2024: Thermo Fisher Scientific established a new manufacturing practice (cGMP) facility in Bleiswijk, Netherlands, bolstering its European clinical trial capabilities for advanced therapies. The site offers comprehensive support for cell and gene therapies, emphasizing sustainable operations towards achieving net-zero emissions by 2050.
  • May-2024: Thermo Fisher Scientific launched the Applied Biosystems Axiom BloodGenomiX Array, designed for accurate blood genotyping in clinical research. This innovative platform covers over 40 genes and more than 260 antigens, detecting both HLA and HPA types with an impressive concordance rate of 99.89%.
  • Dec-2022: Agilent's Resolution ctDx FIRST has received FDA approval as a companion diagnostic for KRAS G12C mutations in advanced non-small cell lung cancer (NSCLC), facilitating treatment decisions for patients eligible for KRAZATI (adagrasib). Developed with Mirati Therapeutics, this liquid biopsy NGS assay offers broad genomic profiling for NSCLC patients.
  • Sep-2023: Thermo Fisher Scientific and the National Minority Quality Forum are partnering through ARC to improve access to clinical research for historically underserved communities. The collaboration aims to promote diversity in trials and facilitate equitable healthcare access initiatives.
  • Sep-2023: Thermo Fisher Scientific introduces the TSX Universal Series ULT Freezers, featuring enhanced performance, energy efficiency, and adaptability across lab settings. Certified by ENERGY STAR® and designed for sustainability, these freezers support diverse scientific workflows and stringent quality standards.

List of Key Companies Profiled

  • Thermo Fisher Scientific, Inc.
  • Merck KGaA
  • Agilent Technologies, Inc.
  • Bio-Rad Laboratories, Inc.
  • Promega Corporation
  • New England Biolabs, Inc.
  • Qiagen N.V
  • Hoffmann-La Roche Ltd.
  • Takara Bio Inc. (Takara Holdings Inc.)
  • Lonza Group Ltd. (Capsugel)

Competent Cells Market Report Segmentation

By Type

  • Chemically Competent Cells
  • Electrocompetent Cells
  • Ultracompetent Cells

By Application

  • Cloning
  • Protein Expression
  • Mutagenesis
  • Others

By End-Use

  • Pharmaceutical & Biotechnology Companies
  • Academic & Research Institutes
  • Others

By Geography

  • North America
    • US
    • Canada
    • Mexico
    • Rest of North America
  • Europe
    • Germany
    • UK
    • France
    • Russia
    • Spain
    • Italy
    • Rest of Europe
  • Asia Pacific
    • China
    • Japan
    • India
    • South Korea
    • Australia
    • Malaysia
    • Rest of Asia Pacific
  • LAMEA
    • Brazil
    • Argentina
    • UAE
    • Saudi Arabia
    • South Africa
    • Nigeria
    • Rest of LAMEA

Frequently Asked Questions About This Report

This Market size is expected to reach $3.7 billion by 2031.

Growing demand for recombinant DNA technology are driving the Market in coming years, however, High initial costs restraints the growth of the Market.

Thermo Fisher Scientific, Inc., Merck KGaA, Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Promega Corporation, New England Biolabs, Inc., Qiagen N.V, F. Hoffmann-La Roche Ltd., Takara Bio Inc. (Takara Holdings Inc.) and Lonza Group Ltd. (Capsugel)

The expected CAGR of this Market is 7.9% from 2024 to 2031.

The Cloning segment led the Market by Application in 2023; thereby, achieving a market value of $1.5 billion by 2031.

The North America region dominated the Market by Region in 2023, and would continue to be a dominant market till 2031; thereby, achieving a market value of $1.3 billion by 2031.

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