The North America Synthetic Small Molecule API Market would witness market growth of 4.9% CAGR during the forecast period (2022-2028).
For oral small molecule medication candidates, a somewhat lower molecular weight cutoff of 500 Daltons has been suggested based on the observation that if the molecular weight is kept below this threshold, clinical attrition rates are dramatically reduced.
In addition to endogenous or exogenous small molecules that can bind to the active site or the allosteric site, enzymes and receptors can also be activated or inhibited by endogenous or exogenous proteins. A useful investigative tool is the plant terpene phorbol 12-myristate 13-acetate, a teratogen, and carcinogen that activates protein kinase C and causes cancer.
There is also interest in developing small molecule synthetic transcription factors to control gene expression, instances include wrenchnolol. A range of analytical techniques, including surface plasmon resonance, microscale thermophoresis, and dual polarization interferometry, can be used to evaluate the affinities and kinetics of the reaction as well as any induced conformational changes.
U.S. economic recovery and changing demand patterns have put pressure on supply chains for other important products, like lumber. In addition, a Green-by-Design strategy is being used to ship environmentally friendly small molecule Active Pharmaceutical Ingredients (APIs). To set goals and monitor process improvements, accurate metrics are essential throughout the development cycle. This examines a few of the several tools and techniques developed to evaluate a process's greenness and sustainability. The advancement in technologies propels the growth of the synthetic small molecule API market.
The US market dominated the North America Synthetic Small Molecule API Market by Country in 2021; thereby, achieving a market value of $50,880 million by 2028. The Canada market is exhibiting a CAGR of 7.3% during (2022 - 2028). Additionally, The Mexico market is experiencing a CAGR of 6.4% during (2022 - 2028).
Based on Manufacturer, the market is segmented into In-house and Outsourced. Based on Application, the market is segmented into Cardiology, Oncology, CNS & Neurology, Endocrinology, Orthopedic, Gastroenterology, Pulmonology, Nephrology, Ophthalmology, and Others. Based on countries, the market is segmented into U.S., Mexico, Canada, and Rest of North America.
Free Valuable Insights: The Global Synthetic Small Molecule API Market is Estimated to reach $187.8 Billion by 2028, at a CAGR of 5.4%
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Merck & Co., Inc., Viatris, Inc., Cipla Limited, Teva Pharmaceuticals Industries Ltd., Sun Pharmaceuticals Industries Ltd., AbbVie, Inc., Bristol Myers Squibb Company, Boehringer Ingelheim International GmbH, Aurobindo Pharma Limited and Albermale Corporation.
Scope of the Study
Market Segments Covered in the Report:
By Manufacturer
By Application
- Cardiology
- Oncology
- CNS & Neurology
- Endocrinology
- Orthopedic
- Gastroenterology
- Pulmonology
- Nephrology
- Ophthalmology
- Others
By Country
- US
- Canada
- Mexico
- Rest of North America
Key Market Players
List of Companies Profiled in the Report:
- Merck & Co., Inc.
- Viatris, Inc.
- Cipla Limited
- Teva Pharmaceuticals Industries Ltd.
- Sun Pharmaceuticals Industries Ltd.
- AbbVie, Inc.
- Bristol Myers Squibb Company
- Boehringer Ingelheim International GmbH
- Aurobindo Pharma Limited
- Albermale Corporation
Chapter 1. Market Scope & Methodology
1.1 Market Definition
1.2 Objectives
1.3 Market Scope
1.4 Segmentation
1.4.1 North America Synthetic Small Molecule API Market, by Manufacturer
1.4.2 North America Synthetic Small Molecule API Market, by Application
1.4.3 North America Synthetic Small Molecule API Market, by Country
1.5 Methodology for the research
Chapter 2. Market Overview
2.1 Introduction
2.1.1 Overview
2.1.1.1 Market Composition & Scenarios
2.2 Key Factors Impacting the Market
2.2.1 Market Drivers
2.2.2 Market Restraints
Chapter 3. North America Synthetic Small Molecule API Market by Manufacturer
3.1 North America In-house Market by Country
3.2 North America Outsourced Market by Country
Chapter 4. North America Synthetic Small Molecule API Market by Application
4.1 North America Cardiology Market by Country
4.2 North America Oncology Market by Country
4.3 North America CNS & Neurology Market by Country
4.4 North America Endocrinology Market by Country
4.5 North America Orthopedic Market by Country
4.6 North America Gastroenterology Market by Country
4.7 North America Pulmonology Market by Country
4.8 North America Nephrology Market by Country
4.9 North America Ophthalmology Market by Country
4.1 North America Others Market by Country
Chapter 5. North America Synthetic Small Molecule API Market by Country
5.1 US Synthetic Small Molecule API Market
5.1.1 US Synthetic Small Molecule API Market by Manufacturer
5.1.2 US Synthetic Small Molecule API Market by Application
5.2 Canada Synthetic Small Molecule API Market
5.2.1 Canada Synthetic Small Molecule API Market by Manufacturer
5.2.2 Canada Synthetic Small Molecule API Market by Application
5.3 Mexico Synthetic Small Molecule API Market
5.3.1 Mexico Synthetic Small Molecule API Market by Manufacturer
5.3.2 Mexico Synthetic Small Molecule API Market by Application
5.4 Rest of North America Synthetic Small Molecule API Market
5.4.1 Rest of North America Synthetic Small Molecule API Market by Manufacturer
5.4.2 Rest of North America Synthetic Small Molecule API Market by Application
Chapter 6. Company Profiles
6.1 Merck & Co., Inc.
6.1.1 Company Overview
6.1.2 Financial Analysis
6.1.3 Segmental and Regional Analysis
6.1.4 Research & Development Expenses
6.1.5 Recent strategies and developments:
6.1.5.1 Partnerships, Collaborations, and Agreements:
6.2 Viatris, Inc.
6.2.1 Company Overview
6.2.2 Financial Analysis
6.2.3 Segmental and Regional Analysis
6.2.4 Research & Development Expense
6.3 Cipla Limited
6.3.1 Company Overview
6.3.2 Financial Analysis
6.3.3 Regional Analysis
6.3.4 Research & Development Expense
6.4 Teva Pharmaceutical Industries Ltd.
6.4.1 Company Overview
6.4.2 Financial Analysis
6.4.3 Regional Analysis
6.4.4 Research & Development Expenses
6.5 Sun Pharmaceuticals Industries Ltd.
6.5.1 Company Overview
6.5.2 Financial Analysis
6.5.3 Regional Analysis
6.5.4 Research & Development Expenses
6.6 AbbVie, Inc.
6.6.1 Company Overview
6.6.2 Financial Analysis
6.6.3 Regional Analysis
6.6.4 Research & Development Expense
6.7 Bristol Myers Squibb Company
6.7.1 Company Overview
6.7.2 Financial Analysis
6.7.3 Regional Analysis
6.7.4 Research & Development Expenses
6.8 Boehringer Ingelheim International Gmbh
6.8.1 Company Overview
6.8.2 Financial Analysis
6.8.3 Regional & Segmental Analysis
6.8.4 Research & Development Expenses
6.9 Aurobindo Pharma Limited
6.9.1 Company Overview
6.9.2 Financial Analysis
6.9.3 Regional Analysis
6.9.4 Research & Development Expense
6.10. Albemarle Corporation
6.10.1 Company Overview
6.10.2 Financial Analysis
6.10.3 Segmental Analysis
6.10.4 Research & Development Expenses
TABLE 1 North America Synthetic Small Molecule API Market, 2018 - 2021, USD Million
TABLE 2 North America Synthetic Small Molecule API Market, 2022 - 2028, USD Million
TABLE 3 North America Synthetic Small Molecule API Market by Manufacturer, 2018 - 2021, USD Million
TABLE 4 North America Synthetic Small Molecule API Market by Manufacturer, 2022 - 2028, USD Million
TABLE 5 North America In-house Market by Country, 2018 - 2021, USD Million
TABLE 6 North America In-house Market by Country, 2022 - 2028, USD Million
TABLE 7 North America Outsourced Market by Country, 2018 - 2021, USD Million
TABLE 8 North America Outsourced Market by Country, 2022 - 2028, USD Million
TABLE 9 North America Synthetic Small Molecule API Market by Application, 2018 - 2021, USD Million
TABLE 10 North America Synthetic Small Molecule API Market by Application, 2022 - 2028, USD Million
TABLE 11 North America Cardiology Market by Country, 2018 - 2021, USD Million
TABLE 12 North America Cardiology Market by Country, 2022 - 2028, USD Million
TABLE 13 North America Oncology Market by Country, 2018 - 2021, USD Million
TABLE 14 North America Oncology Market by Country, 2022 - 2028, USD Million
TABLE 15 North America CNS & Neurology Market by Country, 2018 - 2021, USD Million
TABLE 16 North America CNS & Neurology Market by Country, 2022 - 2028, USD Million
TABLE 17 North America Endocrinology Market by Country, 2018 - 2021, USD Million
TABLE 18 North America Endocrinology Market by Country, 2022 - 2028, USD Million
TABLE 19 North America Orthopedic Market by Country, 2018 - 2021, USD Million
TABLE 20 North America Orthopedic Market by Country, 2022 - 2028, USD Million
TABLE 21 North America Gastroenterology Market by Country, 2018 - 2021, USD Million
TABLE 22 North America Gastroenterology Market by Country, 2022 - 2028, USD Million
TABLE 23 North America Pulmonology Market by Country, 2018 - 2021, USD Million
TABLE 24 North America Pulmonology Market by Country, 2022 - 2028, USD Million
TABLE 25 North America Nephrology Market by Country, 2018 - 2021, USD Million
TABLE 26 North America Nephrology Market by Country, 2022 - 2028, USD Million
TABLE 27 North America Ophthalmology Market by Country, 2018 - 2021, USD Million
TABLE 28 North America Ophthalmology Market by Country, 2022 - 2028, USD Million
TABLE 29 North America Others Market by Country, 2018 - 2021, USD Million
TABLE 30 North America Others Market by Country, 2022 - 2028, USD Million
TABLE 31 North America Synthetic Small Molecule API Market by Country, 2018 - 2021, USD Million
TABLE 32 North America Synthetic Small Molecule API Market by Country, 2022 - 2028, USD Million
TABLE 33 US Synthetic Small Molecule API Market, 2018 - 2021, USD Million
TABLE 34 US Synthetic Small Molecule API Market, 2022 - 2028, USD Million
TABLE 35 US Synthetic Small Molecule API Market by Manufacturer, 2018 - 2021, USD Million
TABLE 36 US Synthetic Small Molecule API Market by Manufacturer, 2022 - 2028, USD Million
TABLE 37 US Synthetic Small Molecule API Market by Application, 2018 - 2021, USD Million
TABLE 38 US Synthetic Small Molecule API Market by Application, 2022 - 2028, USD Million
TABLE 39 Canada Synthetic Small Molecule API Market, 2018 - 2021, USD Million
TABLE 40 Canada Synthetic Small Molecule API Market, 2022 - 2028, USD Million
TABLE 41 Canada Synthetic Small Molecule API Market by Manufacturer, 2018 - 2021, USD Million
TABLE 42 Canada Synthetic Small Molecule API Market by Manufacturer, 2022 - 2028, USD Million
TABLE 43 Canada Synthetic Small Molecule API Market by Application, 2018 - 2021, USD Million
TABLE 44 Canada Synthetic Small Molecule API Market by Application, 2022 - 2028, USD Million
TABLE 45 Mexico Synthetic Small Molecule API Market, 2018 - 2021, USD Million
TABLE 46 Mexico Synthetic Small Molecule API Market, 2022 - 2028, USD Million
TABLE 47 Mexico Synthetic Small Molecule API Market by Manufacturer, 2018 - 2021, USD Million
TABLE 48 Mexico Synthetic Small Molecule API Market by Manufacturer, 2022 - 2028, USD Million
TABLE 49 Mexico Synthetic Small Molecule API Market by Application, 2018 - 2021, USD Million
TABLE 50 Mexico Synthetic Small Molecule API Market by Application, 2022 - 2028, USD Million
TABLE 51 Rest of North America Synthetic Small Molecule API Market, 2018 - 2021, USD Million
TABLE 52 Rest of North America Synthetic Small Molecule API Market, 2022 - 2028, USD Million
TABLE 53 Rest of North America Synthetic Small Molecule API Market by Manufacturer, 2018 - 2021, USD Million
TABLE 54 Rest of North America Synthetic Small Molecule API Market by Manufacturer, 2022 - 2028, USD Million
TABLE 55 Rest of North America Synthetic Small Molecule API Market by Application, 2018 - 2021, USD Million
TABLE 56 Rest of North America Synthetic Small Molecule API Market by Application, 2022 - 2028, USD Million
TABLE 57 KEY INFORMATION - MERCK & CO., INC.
TABLE 58 key information – Viatris, Inc.
TABLE 59 Key Information – Cipla Limited
TABLE 60 Key Information – Teva Pharmaceuticals Industries Ltd.
TABLE 61 Key Information – Sun Pharmaceuticals Industries Ltd.
TABLE 62 Key information – AbbVie, Inc.
TABLE 63 Key Information – Bristol Myers Squibb Company
TABLE 64 Key Information – Boehringer Ingelheim International GmbH
TABLE 65 key information – Aurobindo Pharma Limited
TABLE 66 Key Information – Albemarle Corporation
List of Figures
FIG 1 Methodology for the research